Evaluation of expression and function of vascular endothelial growth factor receptor 2, platelet derived growth factor receptors-alpha and -beta, KIT, and RET in canine apocrine gland anal sac adenocarcinoma and thyroid carcinoma

Urie BK, Russell DS, Kisseberth WC, et al. BMC Vet Res 2012;8:67. ABSTRACT: BACKGROUND: Toceranib phosphate (Palladia) has a reported objective response rate of 25% in both canine apocrine gland anal sac adenocarcinoma (AGASACA) and thyroid carcinoma (TC), with stable … Read More

Pharmacological evidence that spinal alpha(2C)- and, to a lesser extent, alpha(2A)-adrenoceptors inhibit capsaicin-induced vasodilatation in the canine external carotid circulation

Villalon CM, Galicia-Carreon J, Gonzalez-Hernandez A, et al.  Eur J Pharmacol 2012;683:204-210. During a migraine attack capsaicin-sensitive trigeminal sensory nerves release calcitonin gene-related peptide (CGRP), producing cranial vasodilatation and central nociception; hence, trigeminal inhibition may prevent this vasodilatation and abort … Read More

Silent pituitary corticotroph carcinoma in a young dog

Gestier S, Cook RW, Agnew W, et al.  Journal of comparative pathology 2012;146:327-331. An 11-month-old neutered female weimaraner was humanely destroyed 6 days after an acute onset of neurological signs. At necropsy examination the pituitary gland was replaced by a … Read More

Nuclear Imaging In Veterinary Endocrinology

Daniel G. in Conference Proceedings. American College of Veterinary Internal Medicine 2012;700-702. Scintigraphic studies are used in veterinary medicine to image thyroid, parathyroid, adrenal and pancreatic diseases. By far, the most common of these studies is thyroid scintigraphy. Thyroid scintigraphy … Read More

A systematic review of the safety of potassium bromide in dogs

Baird-Heinz HE, Van Schoick AL, Pelsor FR, et al. J Am Vet Med Assoc 2012;240:705-715. Objective-To critically evaluate and summarize available information on the safety of potassium bromide in dogs. Design-Systematic review. Sample-111 references reporting safety information relevant to potassium … Read More

Dietary hyperthyroidism in dogs

Kohler B, Stengel C, Neiger R. J Small Anim Pract 2012;53:182-184. Objectives: Evaluation of dogs with elevated plasma thyroxine concentration fed raw food before and after changing the diet. Method: Between 2006 and 2011 all dogs presented with an elevated … Read More

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