Goggin JM, Hoskinson JJ, Carpenter JW, et al.
To assess the role of scintigraphic evaluation of distal limb perfusion, the medical records and scintigraphic perfusion images of 17 animals (8 dogs, 2 cats, 2 calves, 4 birds and 1 ferret) with clinical signs of distal limb ischemia were examined retrospectively. Images were obtained at 5 and 10 minutes following injection of 99mTc-MDP, or 99mTc-DTPA. The initial scintigraphic diagnoses of 17 animals included complete ischemia (8/17), partially reduced perfusion (5/17), and normal to increased perfusion (4/17). In 4 of the animals with partially reduced perfusion, follow-up scans indicated progression to complete ischemia (1/4) or normal to increased perfusion (3/4). Nine of 17 animals had a final scintigraphic diagnosis of complete distal limb ischemia, and these animals were either euthanized (5/9) or had limb amputation (4/9). A final diagnosis of complete ischemia was supported with either repeat scanning (3/10), continued clinical observation (6/10) and/or pathological examination (10/10). Clinical signs of ischemia resolved in all (7/17) animals with increased or normal perfusion on their final scan. Scintigraphy provided a safe and noninvasive assessment of distal limb perfusion, which corresponded with clinical outcome.