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Radioiodine (I-131)

Hill's Rx y/d Diet

(severely iodine deficient)

Methimazole
OUTCOME
Cures hyperthyroid state
Hyperthyroidism is never cured
Hyperthyroidism is never cured
SIDE EFFECTS
None
Unknown
Common
COSTS
One time
Ongoing for the life of the cat
Ongoing for the life of the cat
CONCURRENT DISEASE
Diet flexible to accommodate
other needs
Strict adherence to Y/D diet required
Diet flexible to accommodate
other needs
TREATMENT
Single SQ injection
Life-long diet
Life-long treatment
HYPOTHYROIDISM
Rare with customized I-131 dosing
Unknown
Common
FOLLOW UP CARE
Routine
Continuous
Continuous
MULTI-CAT HOUSEHOLDS
No impact
Requires independent
feeding of hyperthyroid patient
No impact
ADENOMA
Destroys adenoma
Adenoma continues to grow
leading to possible loss of control
Adenoma continues to grow requiring regular dose adjustments
MALIGNANT TRANSFORMATION
Prevents malignant transformation
Malignant transformation
not prevented
Malignant transformation
not prevented
CARCINOMA
Only effective treatment for cats with thyroid carcinoma
Allows thyroid carcinoma
to progress
Allows thyroid carcinoma
to progress
HYPERTENSION
Renal hypertension and
proteinuria resolve
glomerular hypertension and proteinuria may persist
Renal hypertension and proteinuria may persist
RENAL DISEASE
Stops progression
Poor control may allow progression
Poor control may allow progression
DIET
Variable Diet
Strict diet adherence required
Variable Diet
OBLIGATE CARNIVORE
Meat based diets allowed
High carbohydrate diet inappropriate for obligate
carnivore.
Meat based diets allowed
SURVIVAL
Best long term survival
Survival unproven

Shortest survival
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