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RADIOIODINE
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METHIMAZOLE
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Cures hyperthyroid state
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Hyperthyroidism is never cured, only controlled
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One time cost; no surprise charges or ongoing expenses
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Ultimately, the most expensive method of therapy, costing more than surgery or radioiodine
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No side effects
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Side effects very common
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Single subcutaneous injection
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Life-long daily oral or transdermal treatment
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Routine follow-up care
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Frequent monitoring required
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Post-treatment hypothyroidism rare
with customized I-131 dosing
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Induction of hypothyroidism common
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Destroys thyroid tumors regardless of size
or location, including ectopic tumor tissue
(i.e., sublingual to intrathoracic)
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Thyroid tumor continues to grow requiring regular dose adjustments; may make regulation impossible
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High-dose radioiodine can destroy invasive
and metastatic thyroid carcinoma
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Thyroid tumor can undergo malignant
transformation and invade or metastasize during
long-term medical treatment
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Only effective treatment for cats with thyroid carcinoma
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Not effective in cats with thyroid carcinoma
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Renal hypertension and proteinuria resolve
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Unless well-regulated, glomerular
hypertension and proteinuria persist
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Stops progression of renal disease
associated with hyperthyroidism
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Unless perfectly regulated, persistent renal
hypertension may cause progression of renal failure
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Longest survival
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Shortest survival
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